3-Nitrophthalic anhydride

Product Name: 3-Nitrophthalic anhydride
CAS No.: 641-70-3
Chemical Name: 3-Nitrophthalic anhydride
Synonyms: 1,3-Isobenzofurandione, 4-nitro-;3-Nitrophthalic Acid Anhydride;4-NITRO-ISOBENZOFURAN-1,3-DIONE;NSC 4134;NSC 27006;3-NitrophthaL;Pomalidomide INT;Apremilast Impurity 90;Pomalidomide Impurity 36;3-NITROPHTHALIC ANHYDRIDE
CBNumber: CB8116378
Molecular Formula: C8H3NO5
Formula Weight: 193.11
MOL File: 641-70-3.mol

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3-Nitrophthalic anhydride Property

Melting point:: 163-165 °C (lit.)
Boiling point:: 329.3°C (rough estimate)
Density: 1.6392 (rough estimate)
refractive index: 1.4700 (estimate)
storage temp.: Store below +30°C.
form: Crystalline Powder
color: Beige to yellow
Water Solubility: MAY DECOMPOSE
Sensitive: Moisture Sensitive
BRN: 179963
CAS DataBase Reference: 641-70-3(CAS DataBase Reference)
NIST Chemistry Reference: 3-Nitrophthalic anhydride(641-70-3)
EPA Substance Registry System: 1,3-Isobenzofurandione, 4-nitro- (641-70-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
F: 10-21
TSCA: Yes
HS Code: 29173980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.20903
Product name: 3-Nitrophthalic anhydride
Purity: for synthesis
Packaging: 25g
Price: $87.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.20903
Product name: 3-Nitrophthalic anhydride
Purity: for synthesis
Packaging: 100g
Price: $164
Updated: 2024/03/01

Sigma-Aldrich

Product number: 156884
Product name: 3-Nitrophthalic anhydride
Purity: 98%
Packaging: 5g
Price: $76.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 156884
Product name: 3-Nitrophthalic anhydride
Purity: 98%
Packaging: 25g
Price: $148.8
Updated: 2024/03/01

TCI Chemical

Product number: N0245
Product name: 3-Nitrophthalic Anhydride
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $33
Updated: 2024/03/01

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3-Nitrophthalic anhydride Chemical Properties,Usage,Production

Chemical Properties

Beige to yellow crystalline powder

Uses

An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones.

Uses

4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.

Preparation

3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound.

Purification Methods

Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.]

3-Nitrophthalic anhydride Preparation Products And Raw materials

Raw materials

3-Nitrophthalic acid

Preparation Products

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3-Nitrophthalic anhydride Suppliers

Americas 1 Belgium 2 Canada 2 CHINA 297 Europe 1 France 1 Germany 7 India 23 Japan 4 Poland 1 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 17 United States 48 Global 408

Pure Chemistry Scientific Inc.

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Aladdin Scientific

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Aceschem Inc.

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View Lastest Price from 3-Nitrophthalic anhydride manufacturers

Hebei Kangcang new material Technology Co., LTD

Product: 3-Nitrophthalic anhydride 641-70-3
Price: US $9.00-80.00/g
Min. Order: 10g
Purity: min99%
Supply Ability: 10 tons
Release date: 2024-03-26

Asia Chem I and E (Jiangsu) Co Ltd

Product: 3-Nitrophthalic anhydride 641-70-3
Price: US $62.79/Kg/Drum
Min. Order: 25Kg/Drum
Purity: 98.00%HPLC
Supply Ability: 8.8tons/month
Release date: 2021-09-23

Hebei Guanlang Biotechnology Co,.LTD

Product: 3-Nitrophthalic anhydride 641-70-3
Price: US $10.70/Kg/Bag
Min. Order: 10g
Purity: 99%
Supply Ability: 10000kg
Release date: 2021-08-19

641-70-3, 3-Nitrophthalic anhydrideRelated Search:

3-Fluorophthalic anhydride 4-BROMO PHTHALIC ANHYDRUS Dimethyl phthalate cis-1,2,3,6-Tetrahydrophthalic anhydride Isatoic Anhydride 2-Nitrobenzoic acid 2-Nitrobenzaldehyde CIS-BUTENEDIOIC ANHYDRIDE PHTHALAMIDE O-Phthalimide Dibutyl phthalate Phthalonitrile Phthalic anhydride 3-Nitrophthalic acid 3-Nitrophthalhydrazide 3-Nitrophthalimide METHYL 2-NITROBENZOATE 3-(METHOXYMETHYL)ANILINE

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3-Nitrophthalic anhydride, synthesis grade

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1-Amino-2-Indolinon (CIS)

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3-NITROPHTHALIC ANHYDRIDE ,99+%

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3-NitrophthalicAnhydride&gt

3-NITROPHTHALIC ANHYDRIDE FOR SYNTHESIS

Pomalidomide INT

Pomalidomide Impurity 36

RSSYY(Perospirone Hydrochloride Hydrate)-9

3-Nitrophthalic anhydride?New

Apremilast Impurity 90

641-70-3

C8H3NO5

O2NC6H3CO2O

Organic Building Blocks

Carbonyl Compounds

Carboxylic Acid Anhydrides

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Anhydride Monomers

Monomers

Polymer Science

Carbonyl Compounds

Carboxylic Acid Anhydrides

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Building Blocks

Carbonyl Compounds

Carboxylic Acid Anhydrides

Chemical Synthesis

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Amines

Aromatics

Intermediates

Phthalic Acids, Esters and Derivatives

Dyes intermediates